The conditions covered include, amongst others, depression, schizophrenia, panic, posttraumatic stress disorder, obsessive-compulsive disorder, attention-deficit hyperactivity disorder, and eating disorders. Each chapter provides information about optimal first line pharmacological interventions, maintenance pharmacotherapy and the management of treatment-refractory patients. Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project. Effectiveness and Efficiency: Random Reflections on Health Services. Evidence-based pharmacotherapy of posttraumatic stress disorder Jonathan C. In this introductory chapter, a brief background to evidence-based medicine is provided.
The chapter outlines a definition of evidence-based medicine, considers some of the limitations of evidence-based medicine, discusses the growing emphasis on evidence-based guidelines and algorithms, and notes some of the evidence for evidence-based medicine. Using evidence to inform health policy: case study. This volume examines these issues with reference to the major psychiatric conditions and addresses issues such as selecting the best first-line psychopharmacological intervention for a particular disorder, for how long a particular intervention should be continued, and identifying the next-best treatment strategy should the first agent fail. Evidence-based pharmacotherapy of eating disorders Martine F. Evidence-based pharmacotherapy of illicit substance use disorders Wim van den Brink; 13. Baldwin, Sarah Waldman and Christer Allgulander; 8. Barriers and bridges to evidence based clinical practice.
We therefore felt that it was timely to publish a collection of evidence-based articles in psychopharmacology. Second, there may be lack of effective dissemination and consequent poor access to recommendations. . It may be crucial to target guidelines and algorithms in particular ways for particular users and purposes Stein et al. Guidelines and algorithms Together with the growth of evidence-based medicine there has been the publication of a growing number of guidelines and algorithms, including those in the area of psychiatry and psychopharmacology. Evidence-based Psychopharmacology Cambridge University Press 0521824818 - Evidence-based Psychopharmacology - by Dan J. Despite the current limitations of the field, there are good reasons for accepting that this will ultimately benefit the practice of clinical psychopharmacology.
Educational outreach visits: effects on professional practice and health care outcomes. Guidelines and algorithms are particularly useful insofar as they summarize the evidence including data on efficacy, on effectiveness, and on cost-effectiveness , and point out areas where there are insufficient data and so where further research is needed Patel et al. British Journal of General Practice, 49, 205—10. There are far fewer trials demonstrating the effectiveness of medication in the clinical context, where patient samples are much more heterogeneous than those who enter registration trials Wells, 1999. Evidence-based medicine addresses the question of how best to search the literature, how best to rate the quality of the relevant studies, and how best to synthesize the existing data for example, using meta-analysis Guyatt and Rennie, 2002. American Journal of Psychiatry, 157, 1204—11. British Journal of Psychiatry, 183, 102—4.
All of these have obvious and significant disadvantages. Flament, Hany Bissada and Wendy Spettigue; 11. Presents up-to-date, comprehensive reviews of the psychopharmacological evidence-base for each of the major psychiatric disorders. Ripoll, Joseph Triebwasser and Larry J. Stein 7 Evidence-based pharmacotherapy of social anxiety disorder 137 Carlos Blanco, Muhammad S. British Medical Journal, 319, 1618.
Bernard Lerer is Professor of Psychiatry and Director of the Biological Psychiatric Laboratory at the Hadassah-Hebrew University Medical Center, Jerusalem, Israel. Without clinical expertise, practice risks being tyrannized by evidence. British Journal of Psychiatry, 180, 8—12. Stein is Professor and Chair of the Department of Psychiatry at the University of Cape Town. British Medical Journal, 312, 71—2. The more complex the case, and the greater the specification of individual contributing clinical variables, arguably the less useful any particular guideline will be.
Are benzodiazepines still the medication of choice for patients with panic disorder with or without agoraphobia? Stahl is Adjunct Professor of Psychiatry at the University of San Diego and Honorary Visiting Senior Fellow in Psychiatry at the University of Cambridge. Evidence-based pharmacotherapy of panic disorder Neeltje M. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. Clinical psychopharmacology guidelines: different strokes for different folks. Evidence-based pharmacotherapy of generalised anxiety disorder David S.
These issues lie at the heart of clinical psychopharmacology, making this book invaluable to all practising and trainee clinicians, in a mental health setting or a less specialised environment. Combination therapies and the theoretical limits of evidence-based medicine. All chapters have been fully updated and new contributions on personality disorders and substance dependence added. A useful guideline must walk a fine line between excessive specificity and excessive generality. Contents List of contributors page vii Preface x Introduction xii 1 Evidence-based pharmacotherapy of major depressive disorder 1 Michael J.
New England Journal of Medicine, 342, 1887—92. Evidence-based medicine: what it is and what it isn't. Building on the success of the first edition, the volume summarizes the wealth of new developments in the field and sets them within the context of day-to-day clinical practice. Archives of General Psychiatry, 50, 483—90. The practice of evidence-based medicine involves, however, a good deal more than just the academic exercise of searching for and examining the existing research. This volume presents up-to-date, comprehensive and high quality reviews of the psychopharmacological evidence-base for each of the major psychiatric disorders, written by expert psychopharmacologists from around the world. Evidence-based pharmacotherapy of social anxiety disorder Carlos Blanco, Laura B.